It’s the chronic inflammation of the blocked pilosebiaceous follides; Prevalence is similar in both sexes with the peak age for female is 16-17 year and male 17-19 year.
The selrum secretion invoices due to the hormones – androgen from the testes, ovaries and adrenals. Increased and abnormal keratinisation at the exit of the pilosebaceous follide abstracts the flow of selum. Bacteria play a pathogenic role. Proprionobacterisum acnes are a normal skin commensally. It colonires the pilosebaceous ducts, hreaks down triglyceride releasing free fatty acids, produas seliances chemotactic for inflammalory cells, and induces the ductal epithelium to secret pro-inflammatory cytakines. Rupture of the follide is associated with intense inflammation.
Lesions are limited to the face, shoulder, upper chest and back. Seborrhea (guasy skin) is often present. Open comedones (blackheads) due to plugging lay keratin and seleum of the pilosbaceous orifice, or closed comedones (whitehead) due to accretions of selum and keratin deeper in the ilosebaceous ducts, are always evident. Inflammatory papules, nodules and cysts occur, with one or two types of lesion predominating. Scarring may follow.
The line of treating Ance is to be both local and Hormonal. Oily and spicy with excess of salt should be avoided.
|
